James is very educated in the medicinal use of cannabis and its effect on our Endocannabinoid system (ECS).  With news of Jack Kungel’s reitirement, it would only seem fit that James will be taking place to provide consult for our cannabis community.

The endocannabinoid system (ECS) has emerged as an important neuromodulatory system over the last twenty-five years. Relevant to the topic of this special issue of Biological Psychiatry, perturbations of the ECS are involved in several psychiatric disorders, including schizophrenia. The ECS is comprised of endogenous cannabinoids (endocannabinoids), cannabinoid receptors, and the enzymes responsible for the synthesis and degradation of endocannabinoids (Fig. 1). Each of these components will be introduced in this chapter, with an emphasis on their potential involvement in psychosis.